Hacker Newsnew | past | comments | ask | show | jobs | submit | DANmode's commentslogin

Turmeric always does something.

Whether it’s enough to make a difference in your case depends.


The problem is that this is either unsupported by evidence or a meaninglessly shallow claim. After all, almost every herbal remedy does something, but it doesn't mean it's actually therapeutic for some given condition.

The problem is, you’re out of date regarding the recent efforts put into studying and documenting long-known herbs.

Curcumin is a polyphenol that operates at the molecular level to disrupt multiple inflammatory cascades. It achieves this by simultaneously blocking the transcription of inflammatory genes and interrupting the enzymes responsible for generating pain and swelling.

https://pmc.ncbi.nlm.nih.gov/articles/PMC10111629/

I’ve got a couple other examples I’ve come across recently that I can additionally share.


That paper is co-authored by Bharat B. Aggarwal, who has been found to produce fraudulent research [1], and many of whose papers have been retracted. This is the guy mentioned in the New Scientist article!

Curcumin has been extensively studied, and a common observation is that it is fantastically bioactive in vitro, but tends to have zero meaningful properties when introduced into the biology of a real human being. Researchers have categorized it as an IMPS (invalid metabolic panacea), i.e. a drug whose chemical properties are an illusion, and has ended up becoming a "black hole" for scientific funding [2] [3].

The part about how it "disrupts multiple inflammatory cascades" and so on sounds terrific until you realize these are behaviours observed in vitro. The fact is that curcumin is unstable and highly reactive, so it gets torn apart and neutralized early during digestion, leading to insanely low bioavailability. Tons of compounds are anti-inflammatory in vitro. Very few actually are in the human body.

[1] https://reeserichardson.blog/2024/01/30/the-king-of-curcumin...

[2] https://pubmed.ncbi.nlm.nih.gov/26505758/

[3] https://pubmed.ncbi.nlm.nih.gov/28074653/


Are you sure that means this particular paper is bad?

Fair point, though. Good news, lots of others:

https://pmc.ncbi.nlm.nih.gov/articles/PMC9881416/#S9

https://lpi.oregonstate.edu/mic/dietary-factors/phytochemica...

Also curious how many of those detracting have observed the use of capsules,

or the difference in a person not making proper gut acids / liver function.


No.

You don’t tie it to “your device”.

You tie it to your security key.

Which is treated like a credit card.

and your extended family, friends, or volunteers can act as social proof to allow you back into your accounts,

if your key burns up, it breaks and you were too cool to provision a backup, etc.


Credit cards are lost and stolen all the time, and it isn't really a big deal when it happens, since charges can usually be easily reversed. This does not sound like the same scenario. It also doesn't account for people who lack friends/family nearby or at all.

> it breaks and you were too cool to provision a backup

If we're relying on the average person to back things up properly, this idea is doomed from the start.


> If we're relying on the average person to back things up properly, this idea is doomed from the start.

The average person is relying on the average person, for everything, and I agree, they are doomed from the start.

Tech-related items inclusive.


Yes, you wouldn’t offer your private key to a random food truck.

Just new banks.

Same as people being unafraid of their car key being cloned - because they don’t hand it around the general public.


Is that humor, to you?

They may not wear dark glasses and suits, but these are the peeps who organise disposal if there are not vetted personal to decom it: https://en.wikipedia.org/wiki/DLA_Disposition_Services

This is real, but it's still a joke.


Thank you for teaching.

How are they getting in?

Yikes.

Ah yes, it’s the conspiratorial thinking dividing society,

not humans being humans,

not the people at the highest echelons of society being corrupt (Epstein called).

It’s the people trying to piece that evil together so they know what to tell their kids - they’re the problem.

Sure.


These are tools for people interested in making a change.

You’re not, yet.


I’ve been interested for a decade+, but appreciate the condescension

I’ve found the most effective tool to be uninstalling the apps, being logged out in the browser, then building up a deep resentment for the manipulative practices these apps/sites employ.

Friends send me links on Instagram all the time and it’s always a multi-step process to see it in the browser without being logged in. It’s half-broken and super annoying. If a search query sends me to Instagram, it just breaks 80% of the time and locks me out. If I click on any of the bait designed to lure people into view more content, it will throw up a wall and require downloading the app or logging in. This all serves to fuel the hate I have for these platforms. If they’re going to make it that hard to use, I don’t want to use it, and there must be very powerful and financially motivated reasons why they are pushing me toward a certain engagement model.

I once took screenshots of all the BS I had to go through when he sent me one of those links, so he could see how bad it was and stop spamming me with every other video in his algorithm. At the time it was a 3-4 step process of dismissing modal windows for every link he sent.


You are an average of the 5 people you spend the most time around.

Do those people send you any blog links?

or solely vapid social media shite?

Note that. There’s overlap in other parts of life.


> You are an average of the 5 people you spend the most time around.

Interesting claim, definitely not something valid for me, for better or worse. But I can see why it could be valid in general.


One person who texts me most often primarily sends vapid social media content. I disabled notifications on his texts and check them on my time, skipping most of them. I don't feel the need to cut someone out of my life who I've known for 20+ years over their instagram addiction (which seems to be what you're implying if I read between the lines).

The big AI push has made him more interested in what is happening with all these tech companies and he doesn't like it. I'm trying to use it nudge him off these platforms run by companies he claims to despise.


> I don't feel the need to cut someone out of my life who I've known for 20+ years over their instagram addiction

Then, bluntly, good luck fixing your own problem with the same.

How many decades will you nudge before realizing you’re yelling down a well?

These aren’t new concepts or tricks people are falling for.


I don’t have a problem with it. The only social media adjacent sites I use are YouTube and this one. Any other accounts I had in the past have either been deleted or deactivated for years now.

You’re theory, that my friend using Instagram translates into an addiction for me, doesn’t hold water. I spent 6 years where the 5 people I spent the most time with all smoked, and I’ve never had a cigarette in my life. Values are stronger than peer pressure, especially as an adult. By the end of those 6 years there was only one smoker left.

I’m not sure why you assume I should trend toward an unhealthy habit, instead of him trending toward a healthier habit, especially as his hate for the tech industry grows. I also don’t really care if he quits himself, I just want him to not send so many reels my way. He is already good about not being on his phone when hanging out in person. It’s not that big of a deal.


> I don’t have a problem with it

Then your reply is minorly off-topic, and unexpected, in the context your sibling commenter established.

> You’re theory, that my friend using Instagram translates into an addiction for me

Didn’t say it would cause anything for you. Just that if you had the same issue, it’ll cause you undue friction trying to fix it.


Glad you’re not one of them ;)

Likewise; you seem pretty resistant to positive change, and that’s dangerous to me.

Stay safe.

You can’t fix human problems with technology.

You can only accelerate the human behavior,

unless you involve another person in taking your freedom away.

No condescension - and if you’ve been trying for ten years, there’s clearly a misunderstanding.


> You can’t fix human problems with technology.

Yes you can.

Screen time limiters, nicotine patches, putting the cookies out of sight, all of these things empirically work better than willpower alone.

> No condescension - and if you’ve been trying for ten years, there’s clearly a misunderstanding.

Oh please. “Why are you depressed? Just be happy or you must not be ready for a change. No condescension btw.”


Interesting comparison, because the behavior in question (doomscrolling, inability to manage compulsion, time mismanagement) is definitely linked to ADHD/depression.

Yes, please state your point if you have one.

Treating your health, or having someone close to you tell you it could probably be better, shouldn’t be taboo.

Also, hold the snark, I’m engaging in good faith, here.


Good faith? All you’ve done in this thread is vaguepost and talk down to people who opened up about something they’re struggling with.

You said tech can’t fix human problems. I gave you examples. You dodged with something cryptic about mental health. al_borland said they’re helping a friend off these platforms and you told them “good luck fixing your own problem.” gf263 said they’ve been trying for ten years, and you said they’re “resistant to positive change, and that’s dangerous to me.” Here’s what you’re actually doing: reframing an ordinary struggle as a pathology someone’s in denial about, which puts you above them and turns their disagreement into “resistance.” It’s unfalsifiable. Any tool that works didn’t fix the real problem; anyone who pushes back isn’t ready yet. You’ve built a position where you can’t be wrong and everyone else needs help.

Do you actually want people to solve their problems, or do you just want to talk down to them and feel bigger? Ask yourself who really has the problem here.


> Here’s what you’re actually doing: reframing an ordinary struggle as a pathology someone’s in denial about

Is being wildly overweight also an insurmountable problem that I should not talk about?

Ordinary struggles are often unnecessary, and fixable - yes.

> Ask yourself who really has the problem here.

I’m gonna say - with 100% certainty: the people complaining they can’t stop bringing social media with them to the bathroom.

If what I’ve said is upsetting, put your phone down and look into the mirror.

(Vouched your comment to reply.)


> Yes you can.

I mean, go ahead and tell the user how to fix their problem with software.

They’re the perfect way to prove your point.


> credit card itself can’t be used to ad targeting

Incorrect.

Credit card networks / issuers explicitly describe using payment, spending, and your personal data,

for marketing, personalization, audience segmentation, and advertising.

Mastercard’s privacy notice states that it may use personal and transaction-related information to: “Provide you with personalized services and recommendations” “Offer and support loyalty programs” “Provide content and advertising tailored to your individual interests” “Analyze spending behavior to improve the effectiveness of marketing programs and advertising.”

Visa has also historically offered an opt-out specifically for using card transaction data…


If only I could get rich, structured data access to my spending data... but many banks only allow pdf statement downloads, in inconvenient ways, and their UIs for drilling down into data...

Where can I buy my own data from the brokers?


i meant the credit card number itself

Yes, the card being swiped or entered and or the tokens associated with that card

is the primary key the advertisers are identifying your purchases by,

through the help of the card issuing authority.


Stuff like this that I’ve really enjoyed has gotten permanent AC or portable power.

and it only gets easier and more defined from here.

Guidelines | FAQ | Lists | API | Security | Legal | Apply to YC | Contact

Search: