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> They failed to stop capitalism

good thing, too!


as someone who has a good amount of experience with psychedelics - there is actually a surprising amount of overlap between the two experiences, but mostly in a generalized "how they can feel" way, and not in the sense that they are the same type of experience.

the literature is very clear about the relationship between high LDL and Atherosclerosis. Are you referring to poor health in general, separate from Cardiovascular Disease?

you didn't read the article did you? Or are you actually here to claim that people with hypercholesterolemia just need to eat better?

Do you have the same simplistic ideas about GLP-1's?


For all people? No. For the vast majority of people? Yes. Eat healthy and exercise more.

The dietary impact on cholesterol in the blood is surprisingly low. Looking it up, this source says diet can affect 20-30% of your blood levels [1]. I don’t have a great statistic about exercise, but I’d encourage you to question what you think you know — at the very least I’ll claim you’re mistaken about the importance of dietary impacts on cholesterol, which perhaps should give you pause about your other beliefs

[1] https://my.clevelandclinic.org/health/articles/16867-cholest...


Dietary cholesterol has little impact on blood cholesterol. However the post that started this debate mentioned mass loss. And that does have a decent correlation. Go from obese to not obese and the median person's cholesterol will drop quite a bit.

It’s possible the comments have changed, but I see nothing in the thread about mass loss. I do agree about weight though — losing weight is largely diet.

> Go from obese to not obese and the median person's cholesterol will drop quite a bit.

This is really interesting, I don’t think I’ve heard that before. Do you have a source you could share?

Edit: this doesn’t necessarily prove you wrong, but this paper argues there’s little correlation between bmi and cholesterol [1]

[1] https://link.springer.com/article/10.1007/s11695-010-0170-7


There isn't. I'm 15% body fat, eat healthy (avoid saturated fats, prioritize fiber), exercise 5-6 times per week, and have hypercholesterolemia. I, along with my parents, have very high LDL and ApoB and nothing I can do about it in terms of diet, exercise, or weight.

I'm also not uncommon. They suspect as much of 30% of the population could be like this. There's a lot of ignorance in this thread.


There's a difference between always being hypercholesterolemia as a fit person and being obese and losing a bunch of weight when it comes to these conversations.

It's one f those things where some people's "I can't help it!" claims are true, but many are not. That doesn't invalidate the first category even though most people in the category are in the latter.


> That doesn't invalidate the first category even though most people in the category are in the latter.

so you solved obesity then! people just need to make better choices! Glad we have you here solving the worlds greatest mysteries


for the most part mass == weight on Earth.

Triglycerides & HDL are affected by weight (tho more triglycerides than anything else), e.g. Wing 2011.


> for the most part mass == weight on Earth.

The thread above us discusses neither mass nor weight. Here it is copied in full -- I encourage you to use ctrl-f

> mediumsmart 1 hour ago

> One could eat healthy instead of course but hey, the good life.

> shlant 1 hour ago

> you didn't read the article did you? Or are you actually here to claim that people with hypercholesterolemia just need to eat better?

> Do you have the same simplistic ideas about GLP-1's?

> moi2388 1 hour ago

> For all people? No. For the vast majority of people? Yes. Eat healthy and exercise more

I'm a bit upset that I put in effort to genuinely engage in your claims, and you're not willing to go back and read the thread to confirm claims that _you made_. In fact, you suckered me into re-reading the same thread _for the third time_ looking for some throwaway line I missed about mass or weight. I could just decide that internet discussion doesn't matter, and stop engaging on HN, but I'd rather not do that. Can you please try a bit more?

I'm not going to reply to the Triglycerides & HDL comment without a link. It was your claim initially, and I was nice enough to provide a link with evidence against it, so surely you can do the same in support.


I was responding to the glp-1 question.

And yes, exercising and dieting absolutely reduces the need for these medications.

It also reduces the amount of people who have high cholesterol, although again, in both cases not all


Fiber intake has a dose-dependent effect on cholesterol levels.

Obviously some people still need medication if they have particularly unfortunate genetics.


wow you figured it out! but wait.. if it's that easy why is obesity such a huge issue?

I love that they made the comparison to Hacker News in terms of request sizes lmao. Yea definitely a representative sample


the vast majority of the anti-statin crowd are just regurgitating talking points they heard from people in their diet tribe - usually keto/carnivore


supposedly that comes mostly from observational studies whereas RCT's seem to show that at some point full regain will probably happen (although can take 1-2 years). The Observational studies don't seem to control for people stopping GLP-1's but still trying other drugs/weight loss methods which is where the discrepancy from RCT's seems to be.


> supposedly that comes mostly from observational studies whereas RCT's seem to show that at some point full regain will probably happen

Do you have one you’d recommend reading?


they have long lasting effects if the changes are long lasting. Almost never the case


really? you think it's not significantly effected by anything else? like amount of housing available?


Pretty much no.


and your evidence that property prices are almost entirely set by wages is?


Want to make a bet on what happens to rents in South Padre Island, TX (near SpaceX's Starbase) in the next 6 months?

Want to make a bet on what happens to rents in San Francisco after Anthropic's or OpenAI's rents after they IPO?

There's no reason either event should decrease supply or increase demand, correct? So prices should be stable?


so you don't have any evidence? you are just hoping there will be evidence in the future?

Separately - are you against minimum wage increases as a way to make things more affordable?


Huh? The same dynamic is evident in literally every single leap in productivity and local wages in human history.

Surely if I'm wrong, you're willing to bet on it, correct? Easy money for you? Of course you won't because you obviously know this dynamic is real lmao

https://www.nber.org/papers/w33576

Yes, minimum wage as a way to make things more affordable is mostly a bad idea. https://www.sciencedirect.com/science/article/abs/pii/S00941...

> Increases in state minimum wages significantly reduce the incidence of renters defaulting on their lease contracts by 1.7 percentage points over three months, relative to similar renters who did not experience an increase in the minimum wage. This represents 10.6% fewer monthly defaults. However, this effect slowly decreases over time as landlords react to wage increases by increasing rents.


> The common factor: the capital class screwing over the working class.

This thought terminating cliche is getting real old. What are your solutions? and what evidence do you have that those solutions will solve the problems? Shaking your fists at "the elites" and regurgitating populist slop is not going to


It's the opposite of a thought-terminating cliche. It refers to an entire world and body of work, which include solutions.

You could start by reading Marx, who laid a lot of the groundwork.

> Shaking your fists at "the elites" and regurgitating populist slop is not going to

I like the way you trailed off halfway through your knee-jerk reaction, underscoring just how much your response is an automated result of indoctrination.


Kapital describes the problem well. His proposed solutions were awful.


> It's the opposite of a thought-terminating cliche

> You could start by reading Marx, who laid a lot of the groundwork.

Are you aware that you just responded with another? You did the "read theory" meme lol

> I like the way you trailed off halfway through your knee-jerk reaction, underscoring just how much your response is an automated result of indoctrination

so you don't have solutions or evidence is what I'm gathering? just another lefty populist spouting tired platitudes?


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